Two mysterious women seek refuge in a run-down coastal resort. Clara meets lonely Noel, who provides shelter in his deserted guesthouse, Byzantium. Schoolgirl Eleanor befriends Frank and tells him their lethal secret. They were born 200 years ago and survive on human blood. As knowledge of their secret spreads, their past catches up on them with deathly consequence.
Residents of a coastal town learn, with deathly consequences, the secret shared by the two mysterious women who have sought shelter at a local resort.